Ventricular Arrhythmias Summary

Arrhythmia Types

  • PVC: Premature abnormal QRS ≥120ms
  • VT: ≥3 consecutive beats >100bpm
  • VF: Chaotic rhythm, no discrete QRS

Acute Management

  • Unstable VT: Immediate cardioversion
  • Stable VT: Procainamide/amiodarone
  • VF: Defibrillation, ICD implantation

VT Subtypes

  • Monomorphic: Same QRS morphology
  • Polymorphic: Changing QRS morphology
  • Torsades: Polymorphic + QT prolongation
  • NSVT: 3 beats to 30s duration
  • Sustained: ≥30s or requiring intervention

Idiopathic VT

  • RVOT (75-90%): LBBB, inferior axis
  • Fascicular (10-25%): RBBB, left axis
  • 90% monomorphic VT has structural heart disease

Pharmacological Options

  • General: Procainamide, amiodarone
  • RVOT: Beta-blockers
  • Fascicular: Verapamil
  • Digoxin-induced: Digoxin Immune Fab

Diagnostic Clues

  • AV dissociation
  • Fusion/capture beats
  • No preceding P-wave
  • Broad QRS ≥120ms
  • T-wave opposite QRS direction

Long-term Management

  • ICD for VF (68% risk reduction)
  • Catheter ablation for PVC-triggered VF
  • NSVT: Asymptomatic → monitoring
  • Symptomatic NSVT: Beta-blockers/CCBs

Ventricular Arrhythmias

Ventricular Arrhythmia Subtypes

Premature Ventricular Complex (PVC)

  • Premature occurrence of an abnormal QRS complex
  • QRS duration ≥120ms
  • T-wave typically broad and opposite direction of QRS
  • No preceding P-wave
  • Types:
    • Unifocal/monomorphic - single QRS morphology
    • Multifocal/polymorphic - different QRS morphologies
    • Short-coupled - interrupts T-wave of preceding beat

Ventricular Tachycardia (VT)

  • ≥3 consecutive beats >100bpm from ventricles
  • Types:
    • Non-sustained (NSVT) - 3 beats to 30s
    • Monomorphic (MVT) - same QRS morphology
    • Polymorphic (PVT) - changing QRS morphology
    • Sustained (SMVT/SPVT) - ≥30s or requiring intervention
    • Torsades de pointes - polymorphic VT with QT prolongation

Ventricular Fibrillation (VF)

  • Chaotic rhythm with irregular undulations
  • No discrete QRS complexes

Acute Management of Sustained Monomorphic VT

Unstable Patient

  • Immediate synchronized cardioversion
  • If synchronization not possible, use unsynchronized shock
  • Not indicated for repetitive NSVT

Hemodynamically Stable Patient

  • Consider adenosine/vagal maneuvers if SVT likely (with 12-lead ECG)
  • Prompt termination recommended (electrical, pharmacological, or pacing)
  • Pharmacological options:
    • IV procainamide or amiodarone (unknown etiology)
    • Avoid procainamide in severe HF, acute MI, ESRD
    • For idiopathic VT:
      • Beta-blockers for RVOT tachycardia
      • Verapamil for fascicular VT

Specific VT Types

Idiopathic Fascicular VT

  • 90-95% of idiopathic left VT cases
  • ECG Features:
    • RBBB morphology (RSR' in V1)
    • Left axis deviation (-90°)
    • Narrow-complex capture beats
    • Dissociated P waves
  • Management:
    • Verapamil
    • Digoxin Immune Fab for digoxin-induced
    • Cardioversion if refractory

Right Ventricular Outflow Tract (RVOT) Tachycardia

  • 75-90% of idiopathic VT cases
  • ECG Features:
    • LBBB morphology
    • Inferior axis (+90°)
    • rS in V1, R in V6
    • Precordial transition ≥V3 (septal origin ≤V3)
  • Management:
    • Beta-blockers
    • Cardioversion if refractory

Non-Sustained Ventricular Tachycardia (NSVT)

  • Definition: ≥3 consecutive ventricular beats (QRS ≥120ms, rate >100bpm) resolving in <30s
  • Risk Factors:
    • CAD, LVF, HCM
    • Brugada's, Long QT syndrome
    • Electrolyte imbalance, digoxin toxicity
  • Management:
    • Asymptomatic: reassurance & monitoring
    • Symptomatic: beta-blockers/CCBs
    • Correct electrolyte imbalance
    • ICD if criteria met

Ventricular Fibrillation (VF)

  • Diagnosis: Documented VF after excluding structural/channelopathic causes
  • Workup:
    • ECG (including high lead), cardiac CT/angiography
    • Holter, stress test, echocardiogram
    • Sodium-channel blocker testing, CMR
    • Genetic testing (consider)
  • Management:
    • ICD implantation (68% risk reduction)
    • For recurrent discharges: isoproterenol, verapamil, quinidine
    • Catheter ablation for PVC-triggered VF

Key Clinical Pearls

  • 90% monomorphic VT associated with structural heart disease
  • 10% are idiopathic (75-90% RVOT, 10-25% fascicular)
  • Fascicular VT often misdiagnosed as SVT with RBBB
  • Look for AV dissociation, fusion/capture beats for VT diagnosis